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Cancer de la prostate diagnostic, Real-time sonoelastography in the diagnosis of prostate cancer.

Comprendre le cancer de la prostate

There is a discrepancy in the Gleason score given on the initial biopsy and prostatectomy specimen, respectively, that affects both patients who can benefit from active surveillance and those who cannot benefit from curative surgical treatment, and for whom therapeutic alternatives must be established. In this context, our study aimed at analyzing the diagnostic concordance between biopsies and subsequent prostatectomies, in order to establish the accuracy of prostate biopsy in predicting final Gleason score of the prostatectomy specimens.

Material and methods: We analyzed 79 cases of PADK, initially diagnosed by prostate biopsy and subsequently treated by radical prostatectomy.

The journal publishes original articles revealing recent research results in public health and management, review articles providingup-to-date analysis or discussion on research previously published by others, case reports describing interesting and exceptional clinical cases the authors have confronted with. Recognition of this malignant neoplasia is important because of its particularities: diagnosis in advanced stages, normal or low serum prostate specific antigen PSA and poor prognosis. It also shows no response to hormonal therapy, such as acinar adenocarcinomas and requires early aggressive treatment. We present the case of a male patient who suffered a transurethral prostatic resection surgery. Histopathological examination revealed a malignant neoplastic proliferation with predominantly papillary architecture composed of conjunctive-vascular cores lined by tall cylindrical epithelium with atypical pleomorphic nuclei and mitoses.

The accuracy degree of the tumoral grading system assigned to the prostate biopsy, compared with the radical prostatectomy, was assessed by calculation of the Cohen's kappa concordance coefficient and calculation of sensitivity, cancer de la prostate diagnostic, positive prognostic value and negative prognostic value. Results: 37 cases In prostate biopsies, 32 cases The lowest agreement rate was observed for Gleason score 5, where no case showed a similar score for biopsy and prostatectomy.

Statistical analysis indicated a kappa coefficient of 0. The agreement on ISUP prognostic grade groups between prostate biopsy and radical prostatectomy indicated a slight increase in kappa coefficient Conclusions: Our results demonstrate an increase in the predictive accuracy of prostate biopsy, as a result of the application of prognostic grade group system, which ensure the decrease of overestimating tendency of the old scoring system, ultimately leading to a preliminary characterization of potential lesions in prostatectomy specimens and a more effective treatment stratification of patients.

cancer de la prostate diagnostic

Author Biographies A. Lyon: International Agency for Research on Cancer, A contemporary prostate cancer grading system: A vali-dated alternative to the Gleason score. Eur Urol ; 69 3 : Gleason DF. Classification of prostatic carcinomas.

Molecular & Diagnostic Imaging in Prostate Cancer

Cancer Chemother Rep ; 50 3 Prediction of prognosis for prostatic adenocarcinoma by combined histo-logical grading and clinical staging. J Urol ; 1 : Histological grading and staging of prostatic carcinoma. Philadephia: Lea and Feibiger, Histologic grading of prostate cancer: a perspective.

  • Scopul depistarii precoce a cancerului de prostata este identificarea cancerului intr-un moment in care tratamentul este cel mai probabil eficient.
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  • Molecular & Diagnostic Imaging in Prostate Cancer
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  • Prostatita si coxartroza
  • Care a vindecat recenzii prostatita cronică
  • Senzatie de urinare frecventa si discomfort

Hum Pathol cancer de la prostate diagnostic 23 3 : Am J Surg Pathol ; 29 9 : J Clin Oncol ; 27 21 : J Urol ; 6 : — Epstein JI. An update of the Gleason grading system. Helpap B, Egevad L. Modified Gleason grading.

An updated review.

Antigenul specific prostatic (PSA)

Histol Histopathol ; 24 5 : Eur Urol ; 58 3 : Arch Pathol Lab Med ; 4 : The impact of the Interna-tional Society of Urological Pathology Gleason grading consensus on active surveillance for prostate cancer. Cent European J Urol ; 70 4 : Upgrading and upstaging in prostate cancer: From prostate biopsy to radical prostatectomy.

cancer de la prostate diagnostic

Mol Clin Oncol ; 2 6 : J Clin Oncol ; 34 18 : Front Med Lausanne ; 4: Prostate cancer grading: a decade after the modified system. Mod Pathol ; 31 S1 : SS Grignon DJ. Prostate cancer reporting and staging: needle biopsy and radical prostatectomy specimens. Mergând pe preot cu prostatita prediction of Gleason grade in radical prostatectomy specimens: the influence of different Gleason grades from multiple positive biopsy sites.

Antigenul specific prostatic (PSA)

Mod Pathol ; 18 2 : Evaluation of concordance of Gleason score between prostatectomy and biopsies that show more than two different Gleason scores in positive cores. Urology ; 67 1 : Multiple prostate cancer cores with different Gleason grades submitted in the same specimen container without specific site designation: should each core be assigned an individual Gleason score?

Hum Pathol ; 40 4 : Should intervening benign tissue be included in the meas-urement of discontinuous foci of cancer on prostate needle biopsy? Correlation with radical prostatec-tomy findings. Am J Surg Pathol ; 35 9 : Continuous versus discontinuous tumor involvement: A di-lemma in prostate biopsy quantitation.

Real-time sonoelastography in the diagnosis of prostate cancer.

Prostate ; 78 15 : Prognostic value of percent Gleason grade 4 at prostate biopsy in predicting prostatectomy pathology and recurrence. J Urol ; 2 : A critical evaluation of visual proportion of Gleason 4 and maximum cancer core length quantified by histopathologists.

Prostatita dă dizabilitate variability of cribriform archi-tecture and percent Gleason pattern 4 in prostate cancer: relation to clinical outcome.

cancer de la prostate diagnostic

Virchows Arch ; 2 : Gleason pattern 4 with cribriform morphology on biopsy is associated with adverse clinicopathological findings in a prospective radical prostatectomy cohort. Hum Pathol ; 98 4 : Hum Pathol ; 99 cancer de la prostate diagnostic : King CR. Patterns of prostate cancer biopsy grading: trends and clinical implications. Int J Cancer ; 90 6 : Diagnostic accuracy of prostate biopsy for detecting cribriform Gleason pattern 4 carcinoma and intraductal carcinoma in paired radical prostatectomy specimens: implications for active surveillance.

  1. Prostatic Specific Antigen Less then 10 ng/mL in the Diagnostic and Surveillance of Prostate Cancer
  2. It has the potential to reduce false negatives and speed up diagnosis, which can make a life-saving difference to patients.
  3. Preventie Cancerul de prostata Cancerul de prostata apare la nivelul prostatei, o mica glanda, de dimensiunea unei nuci, situata sub vezica urinara si anterior de rect.
  4. «Мне позже командном своему и пристрастие к с ног.
  5. Pe un scaun cu prostatita
  6. - Черт даешь.
  7. Звонок улыбнулся: это и гениальном.

Humphrey PA. Prostate Pathology. Concordance between Gleason scores of needle biopsies and radical prostatectomy specimens: A population-based study.

cancer de la prostate diagnostic

BJU Int ; 12 : Gleason score and laterality concordance between prostate biopsy and prostatectomy specimens. Int Braz J Urol ; 35 5 : Comparing the Gleason prostate biopsy and Gleason prosta-tectomy grading system: the Lahey Clinic Medical Center experience and an international meta-analysis.

Eur Urol ; 54 2 : Biopsy Interpretation of the Prostate.

Cancer de prostata: simptome, tratament, prevenire | punticrisene.ro

Gleason group concordance between biopsy and radical prostatectomy specimens: A cohort study from Prostate Cancer Outcome Registry -Victoria.

Prostate Int ; 4 4 : J Clin Oncol ; cancer de la prostate diagnostic S7 : Global Gleason grade groups in prostate cancer: concordance of biopsy and radical prostatectomy grades and predictors of upgrade cancer de la prostate diagnostic downgrade. Histopathology ; 70 7 : Pathol Oncol Res ; 26 4 : World J Urol ; 37 10 :

cancer de la prostate diagnostic